Plenty of potential in the Saturn launch system - I’d say the real possibility for problems would be the longevity of the CSM systems. The CSM was designed for lunar missions lasting for much shorter periods than a trip to Venus and back lasting roughly a year. I wonder if the orbital dynamics would’ve worked with what undoubtedly would’ve been a heavier trans-Venus rated CSM. Weight gain would’ve been inevitable in order to ensure enough longevity and redundancy for a 12 month mission. Sure would’ve been a fabulous follow up to the lunar missions and a real steppingstone to deep space capable spacecraft.